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Louisville to St. Louis | 9-Day Voyages

Rates & Dates:

Trip Length: 9 Days/ 8 Nights

Prices from: $1,899 pp/do*

Single Price: $2,849 pp

2017 Dates: July 16

2018 Dates: July 22

Ships: American Queen

Notes: Fares do not include port charges.
*Per Person/Double Occupancy. Special Single Rates apply where listed.

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Or call us: 1-800-578-1479

The American Queen wanders the rivers. On this cruise, it’ll amble down the Ohio, dawdle awhile in the Four-Rivers Area (where the Ohio, Tennessee and Cumberland Rivers flow together into the Mississippi River), then meander north on the Mississippi. While the riverboat lazily drifts along, you’ll have time and opportunity to explore historic river towns, each with their unique culture and identities.

2017 Departures

American Queen: July 16

2018 Departures

American Queen: July 22

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Theme Cruises

The 50s and 60s Remembered: The Grand Saloon will be Rockin’ and Rollin’ as you cruise the Mississippi River on the American Queen! Put on your dancin’ shoes and shake it all night long to the music of the 1950’s and 60’s! From the silky smooth tones of Frank Sinatra and Nat King Cole, to the groovin’ tunes of the Stones, Bob Dylan, Jimi Hendrix and the Beatles, you’ll find the right music to move you on this summer cruise.


American Culinary: Every region of America has their own cuisine, developed through the regional history as different crops and people moved in and out. This cruise through Kentucky, Missouri and Illinois will highlight the diverse culinary legacies of mid-America. Chefs will lead onboard cooking demonstrations, and the cuisine for this cruise has been planned and created just for this departure.

2017 Louisville to St. Louis Departure:

July 16th (Music of the 50’s and 60’s)
Fares start at $1899 pp/do ($2849 single)


2018 Louisville to St. Louis Departure:

July 22nd (American Culinary)

Fares start at $1999 pp/do ($2499 single)



Day 1: Deluxe Hotel Stay in Louisville, KY

Day 2: Embark in Louisville, KY

We’ll embark at 5pm, so enjoy the morning in Louisville! Arrive to your boat rested and ready to enjoy your cruise.

Day 3: Brandenburg, KY

The rolling hills and farmlands surrounding Brandenburg makes it picture perfect! Take a tour General George Patton Museum of Leadership in the fabled Fort Knox.

Day 4: Owensboro, KY

Owensboro, a hidden river gem, is the 4th largest city in Kentucky. Take in natural wonder and beauty at the Western Kentucky Botanical Garden or the Owensboro Area Museum of Science and History. Or experience manmade beauty at the Owensboro Museum of Fine Art or the International Bluegrass Music Museum!

Day 5: Henderson, KY

Henderson was originally created as a railroad stop! After the Civil War, it quickly grew into a real town. It is home to the John James Audubon Museum and State Park, showing off the fascinating history of Audubon and his love of birds. If you’re looking for a place to relax, take a walk around Audubon Mill Park – perfect for a picnic!

Day 6: Paducah, KY

Lowertown Arts District is a great area of Paducah to explore, including the National Quilt Museum – 13,000 sq ft of display space! What American treasures will you find in this small river town?

Day 7: Cape Girardeau, MO

This small town in the river was the inspiration for Mark Twain’s Life on the Mississippi. When you explore, be sure to visit the Cape River Heritage Museum. It’s a great snapshot at the history of the region, the river, and Missouri. Photo Op: Take a picture of yourself in the model steamboat or the tall-ladder fire truck! (Your grandkids will be so jealous!)

Day 8: River Cruising

Enjoy this time to relax and enjoy the beautiful American Queen: visit the Ladies’ Parlor or find a book to read in the Mark Twain Gallery.

Day 9: Disembark in Alton, IL

Look out this morning to see the beautiful arch of St. Louis! We’ll disembark right across the river in Alton.


The 2018 Itinerary differs, visiting Chester, IL and not Owensboro, KY.

Photo Credit: American Queen Steamboat Company