Lower Mississippi River Cruise-American Serenade

Explore historic and modern river life on this unique exploration of the Lower Mississippi River. Cruising from NOLA to Memphis, or reverse, you’ll catch the heartbeat of the river. Enjoy Cajun cuisine on the Mississippi Delta, and so much more!

 

Ports of call include: Oak Alley | Natchez | Baton Rouge | Vicksburg | St. Francisville | Memphis | New Orleans

Cruise Details

Clock9 Days & 8 Nights

Double Occupancy from $5,545 pp/do*

Single Occupancyfrom $7,485 pp

CalendarNovember 12, 2024 | February 21, 2025 | February 28, 2025 | March 7, 2025 | March 14, 2025 | March 21, 2025
See 14 more available dates
March 28, 2025 | April 4, 2025 | April 11, 2025 | April 18, 2025 | April 25, 2025 | May 2, 2025 | May 9, 2025 | May 16, 2025 | May 23, 2025 | May 30, 2025 | June 6, 2025 | October 16, 2025 | October 23, 2025 | November 9, 2025

Book Now Request More Info

or call 800.578.1479

*Per person/double occupancy. Special single rates apply where listed. Excludes port fees.
Itineraries may operate in reverse.

Your Itinerary

    1New Orleans, LA
    Settle into your hotel and enjoy a feast for your senses as you explore this magical city, renowned for its delicious cuisine, vibrant music scene, and rich culture with an international flair. Stroll the tree-lined avenues, take a carriage ride through the French Quarter, hop aboard a streetcar to the gorgeous Garden District, or visit the renowned National World War II Museum.

    2Cruising the Mississippi River
    Board your ship and be treated to a Welcome Reception. Get to know your fellow guests and savor the view as you enjoy the afternoon rolling on the mighty Mississippi. Be entertained by onboard performers who will perform the music born of the river.

    3Houmas House, LA
    Step off your ship docked right at Houmas House and explore one of the most elaborately renovated of the grand homes along the river, once a private home and a thriving historical agricultural enterprise. Entertaining and knowledgeable guides will escort you through the magnificently restored home’s unmatched collection of stunning period furnishings and artwork. The ornately landscaped grounds include 38 acres of gardens, fountains, and majestic live oak trees.

    4Baton Rouge, LA
    Meaning “red stick,” Baton Rouge’s 1699 French name references an ancient geographical marker and reflects the city’s long history. As Louisiana’s state capital, the city still echoes with tales of the characters who lived here, most notably Governor and Senator Huey P. Long. Learn about his dramatic career at the magnificent 1852 Old State Capitol Museum and visit Long’s 1932 State Capitol building, an architectural marvel of granite and marble.

    5St. Francisville, LA
    As the bow-ramp from the ship opens and stretches to the shore, you will be welcomed into the historic cotton port of St. Francisville. Overlooking the river from atop a high, St. Francisville began as a part of Spanish West Florida in the early 1800s until American settlers overthrew the Spanish governing forces, and the region later became part of the United States. Experience this town’s rich history on your own or with a variety of guided excursions. As you explore, discover the Historic District which boasts magnificent mansions and unique boutique shops and admire cottonwood trees which transition to stately oaks adorned with Spanish moss.

    6Natchez, MS
    In Natchez, grand homes sparkle like jewels, adorning the bluffs that tower above the river. Since 1716, when the French first built a fort here among the Natchez Indians, the town has grown to boast elaborate mansions built by planters in the 1800s to flaunt their wealth. With no Civil War fighting here, Natchez still features hundreds of antebellum homes and buildings. Each of these architectural treasures has its own story to tell, creating a charming downtown that embodies the essence of southern charm and hospitality.

    7Vicksburg, MS
    Vicksburg is a place of drama. During the Civil War, the struggle to control Vicksburg proved to be a major turning point. The well-fortified connection between river and rail transportation was known as “The Gibraltar of the West.” A narrated exploration of the well-preserved National Military Park battlefield enlivens this powerful story and highlights its significance. President Abraham Lincoln summarized Vicksburg’s importance clearly when he said, “Vicksburg is the key. The war can never be brought to a close until that key is in our pocket… They can defy us from Vicksburg… As valuable as New Orleans will be to us, Vicksburg will be more so.” Several other excursion options are available, including exploring museums and historic sites with local expert guides or on your own. Walk aboard an enormous Army Corps of Engineers towboat. Stroll along the charming series of murals painted along the adjacent floodwall and read panels detailing the Vicksburg stories they illustrate.

    8Memphis, TN
    Visit historic Beale Street to hear the beat of ‘Blues City’ or head over to Graceland to pay tribute to the King of Rock and Roll, Elvis Presley!

    9Memphis, TN
    Enjoy breakfast onboard the ship, before heading back home. Reflect on your adventures and new friends made along the way.

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Cabin Categories

Cabin Single Price Double Price
Grand Suite (GS)$10,620 pp
Veranda Suite (VS) $8,290 pp
Premium Balcony (PB)$6,995 pp
Deluxe Balcony 1 (DB1)$6,660 pp
Standard Balcony (SB)$5,995 pp
Single Balcony (SGB) $7,620

Ship Read more about the American Serenade

*Prices may vary due to seasonality

Onboard Experience

The American Cruise Line fleet of ships are the newest and most environmentally friendly small ships in the US. The cruise line prides itself on their hospitable staff, and that you’ll be graciously received no matter which ship you cruise on. The large staterooms with interior entrances ensure you have a relaxed, private area to watch the river from, or visit any of the many onboard lounges. Daily entertainment will be brought onboard, including musicians, historians and naturalists.

Regionally-Inspired Menus

American Cruise Lines uses fresh, local ingredients to show off the culinary glory of the region you’re cruising in. On the Mississippi River, that could mean Andouille Gumbo, a po’boy with red beans and rice, and bourbon pecan pie. In New England, you could find Littleneck clam ceviche on the menu followed by a spiced apple pudding with maple whipped cream. In the Pacific Northwest, you’ll find fresh fish on the menu, including shrimp bisque or Dungeness Crab cake, and a marionberry cheesecake that’ll make your mouth water! Your ship will provide you with a list of all the locally-sourced ingredients when you unpack.

Eagle Society

Once you’ve cruised aboard any American Cruise Line ship, you are an Eagle Society member. It’s free to be a member, but your loyalty to American Cruise Lines is greatly rewarded. You’ll receive Eagle Society luggage tags, and member-only gifts when you board each cruise. After 3 cruises, you’ll receive complimentary premium shore excursions. After 10 cruises, you’ll get a complimentary 11th cruise. There are special Eagle Society cruise dates every year. Plus all Eagle Society member benefits can be used when booking with USA River Cruises, plus you’ll still be eligible for our loyal customer benefits as well.

Book Today

Lower Mississippi River Cruise-American Serenade

Book Now Request More Info

or call 800.578.1479

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