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Mississippi River Cruises

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ALL 2016 MISSISSIPPI RIVER CRUISES INCLUDE A 1-NIGHT PRE-CRUISE HOTEL!

The Mighty Mississippi Awaits!

Charmed by the mighty Mississippi River? Our USA River Cruise agents are ready and waiting to help you plan a journey like no other.

The Mississippi River is filled with diverse, culturally-rich regions that promise historical, musical, and gustatory experiences unlike those found anywhere else in the world. For this reason, our cruises are customized to suit the experience you are seeking, whatever that may be. Are you a Civil War buff? Do you treasure the writings of Mark Twain, or love to dance the night away to Louis Armstrong’s jazz classics? Or are you seeking a Mardi Gras full of dance, color, and delicious food?

No matter what aspect of this mighty river and its many facets appeals to you, we have the cruise of your dreams. You’ll enjoy six to 22 days of fabulous food, music, comradery, and relaxation, sitting on the deck of one of our gorgeous paddle wheelers. This fantastic mode of travel slows life down and allows you to soak up every ounce of beauty along this iconic body of water.

Look ahead to 2017, when Viking will bring their historic cruise ships to the Mississippi. Book ahead and be one of the first to enjoy their luxurious steamboats!

Our booking agents are ready to answer any questions you may have and to accommodate any and all special needs. All of our staff are uniquely qualified to customize the trip of a lifetime. Most of us have taken these cruises ourselves and are intimately familiar with every detail of the journey, making us the best possible resource for you. Call us; we’re excited to help you launch!

Cumberland River Cruise: Nashville – St. Louis

Save up to $1500 Off Per Stateroom on Select 2017 Departures!!
Book by: 02/25/2017

The Cumberland River is a historic route of music, cuisine, and love of all things Southern. Cruise along the River on the Queen of the Mississippi paddlewheel, relaxing perhaps in the Sky Lounge- More...

Upper Mississippi River Cruise: St. Louis – St.Paul

Upper Mississippi River Cruise: St. Louis - St.Paul

Save up to $500 Off Per Stateroom on Select 2017 Departures!
Book by: 02/25/2017

Two magnificent paddlewheelers are cruising the Upper Mississippi River: the Queen of the Mississippi and the America (new to the river 2016). Escape the heat of Summer with the cool breezes from the- More...

Bourbon Cruise

New Orleans & Cajun Country

Save up to $800 Off Per Stateroom on Select 2017 Departures!!
Book by: 03/31/2017

Bourbon is Kentucky. Search deep into local history to find the roots of bourbon in the foothills of Kentucky. Experts will guide you as you learn the distinguishing characteristics of bourbon- More...

Holiday-Christmas Markets

Save up to $800 Off Per Stateroom on Select 2017 Departures!!
Book by: 03/31/2017

Think of it: the most opulent riverboat in the world, cruising the Mississippi River, decorated for a Victorian Christmas! The American Queen will be transporting you from New Orleans to Memphis (or- More...

Thanksgiving Aboard the American Queen

Save up to $600 Off Per Stateroom on Select Departures!!
Book by: 03/31/2017

Thanksgiving Aboard the American Queen Give thanks for not having to cook the turkey, do the dishes, or clean up the house for company! Whether you want a holiday to yourself, or you take the- More...

Antebellum South Cruise

Save up to $600 Off Per Stateroom on Select Departures!!
Book by: 03/31/2017

The Old South is about traditions, nostalgia, and hospitality. You'll experience all three on these American Queen cruises. On the lower Mississippi River, you'll visit small river towns, big,- More...

Music of America

Save up to $600 Off Per Stateroom on Select Departures!!
Book by: 03/31/2017

The paddlewheel has its own rhythm but so does the music of the rivers as we float through the myriad melodies of blues, gospel, folk, rockabilly, ragtime, Dixieland jazz and zydeco. Sway to the- More...

New Year’s Eve Aboard the American Queen

New Year's Eve Aboard the American Queen

Book & Pay In full and Save $800 Off Per Stateroom!!
Book by: 03/31/2017

For your new year's resolution, you're going to travel. And to start the year off right, ring in the new year onboard the American Queen! You'll celebrate the entire week, but everyone will gather- More...

Music of the 50s and 60s

Music of the 50s and 60s

Save up to $800 Off Per Stateroom on Select Departures!!
Book by: 03/31/2017

The Grand Saloon will be Rockin' and Rollin' as you cruise the Mississippi River on the American Queen! Put on your dancin' shoes and shake it all night long to the music of the 1950's and 60's! From- More...

Complete Mississippi River Cruise

Paddlewheel chart room

Save up to $2500 Off Per Stateroom on Select Departures!!
Book by: 02/25/2017

Enjoy a complete Mississippi River cruise!- More...

Cruise the Deep South: New Orleans, Round Trip

Save up to $1500 Off Per Stateroom on Select 2017 Departures!!
Book by: 02/25/2017

New Orleans is situated at the mouth of the Mississippi River, guardian of the treasures that abound along the river's edge. Let the America or the Queen of the Mississippi be your river guide,- More...

Lower Mississippi River Cruise: New Orleans – Memphis

Save up to $1500 Off Per Stateroom on Select 2017 Departures!!
Book by: 02/25/2017

Explore historic and modern river life on this unique exploration of the Lower Mississippi River. Cruising from NOLA to Memphis, or reverse, you'll catch the heartbeat of the river. Enjoy Cajun- More...

The Gateways of the Mississippi: New Orleans to St. Louis

Save up to $2000 Off Per Stateroom on Select 2017 Departures!!
Book by: 02/25/2017

This unique itinerary on the Lower Mississippi takes you from the 'Gateway to the West' in St. Louis to New Orleans - our original 'Gateway' to the Mississippi and America's Heartland! Most of- More...

The Mighty Mississippi

New Orleans & Cajun Country

Save up to $2400 Off Per Stateroom on Select Dates!!
Book by: 03/31/2017

The American Queen has one opportunity for you in 2017 that will allow you to cruise the entire length of the Mighty Mississippi River! Total cruise length is 23-days, including a 1-night pre-cruise- More...

Life on the Mississippi

New Orleans & Cajun Country

Save up to $800 Off Per Stateroom on Select 2017 Departures!!
Book by: 03/31/2017

Are you the type of cruiser who just wants to sit back and watch the world float by? Let's cross the Upper Mississippi off your cruise to-do list with this 9-day getaway, roundtrip from Minneapolis.- More...

Ohio River Cruise: St. Louis to Pittsburgh

Save up to $2500 Off Per Stateroom on Select 2017 Departures!!
Book by: 02/25/2017

Time to cruise east, leaving the familiar Mississippi behind for the Ohio River! Follow the history of the pioneers who kept pushing the boundaries of American identity in music, culture,- More...

Chairman’s Cruise

Save up to $800 Off Per Stateroom on Select 2017 Departures!!
Book by: 03/31/2017

Cruise the Ohio River on the Chairman's Cruise. Are you passionate about small ship cruising, river cruising, steamboats or paddlewheels? The Chairman of the American Queen, John Waggoner and his- More...

Cruise the Mississippi Aboard the All-Suite American Duchess

Save up to $800 Off Per Stateroom on Select 2017 Departures!!
Book by: 03/31/2017

2017 will be the inaugural season for the 166-passenger American Duchess - the first all-suite river cruise vessel. Your experience will be what you've come to expect from our all-inclusive small- More...

Big Band Swing Cruise Aboard the American Queen

Big Band Swing Cruise Aboard the American Queen

Big Band Swing has been one of the most popular themes on the American Queen every year for one very special reason: the nostalgia of the swing era (1920s-30s) with live band performances in the- More...

Autumn Colors Aboard the American Queen: Chattanooga to Nashville

Autumn Colors Aboard the American Queen: Chattanooga to Nashville

  Cruising in Autumn is magic! As you roll down the river, watch the colors change across the landscape. Glimpse the white steeples peeking up through the leaves, and the colors run up and- More...

Upper Mississippi River Cruises on the American Queen

Upper Mississippi River Cruises on the American Queen

The upper reaches of the Mississippi River from dynamic St. Louis to the twin cities of Minneapolis and St. Paul are rich with frontier tales of fur traders and pioneers set among picturesque geography and abundant wildlife.- More...

Civil War Theme Aboard the American Queen: Nashville to Chattanooga

Civil War Theme Aboard the American Queen: Nashville to Chattanooga

  There is no more defining moment in the history of the South than the Civil War. The Mississippi River was often at the forefront of the war, because of its strategic advantages for- More...

Grand Heartland Cruise

Grand Heartland Cruise

Time to Check 'Mississippi River' Off Your Bucket List! Are you ready to cruise the entire length of the Mississippi River? You may have cruised segments before, but nothing can compare to- More...

Mark Twain

Mark Twain

Sold Out for 2017! Watch for 2018 Departures. There is nothing more synonymous with the Mississippi River than Mark Twain. Originally born Samuel Longhorne Clemens in Hannibal, Missouri, Mark- More...

Autumn in the Great Smokies | Rail & Sail

Autumn in the Great Smokies | Rail & Sail

The Great Smoky Mountains adorned in fall colors create a striking landscape for your rail and sail vacation! Beginning in Atlanta, you'll enjoy a stay in Asheville before boarding the Great Smoky- More...

Musical Heritage of the Delta

Musical Heritage of the Delta

Become engulfed in the true south: from the fertile cotton fields and vast sugar cane plantations to the pillared mansions and bygone battlefields. Through it all echoes the musical history of the- More...