Minneapolis to New Orleans | 16-Day Voyages

Cruise the entire length of the Mississippi River southbound, from Minneapolis to New Orleans. Enjoy all the wonder and history along the way, visiting bustling cities and small river towns that have stood the test of time.


Visit charming small towns including Dubuque, Red Wing, Vicksburg, and LaCrosse as well as historic cities of Memphis, Natchez, and St. Louis

Cruise Details

Clock16 Days & 15 Nights

Double Occupancy from $6,299 pp/do*

Single Occupancyfrom $7,599 pp

CalendarAugust 11, 2024

Book Now Request More Info

or call 800.578.1479

*Per person/double occupancy. Special single rates apply where listed. Excludes port fees.
Itineraries may operate in reverse.

Your Itinerary

    1Hotel Stay in Minneapolis, MN

    2Embark in Red Wing, MN
    Board the American Queen this morning before our 5pm departure.

    3Winona, MN
    Winona is a stunning, 'Island City,' built upon a large sand bar sitting beneath the limestone river bluffs of the Mississippi!

    4La Crosse, WI
    This city on the river was originally built for the lumber industry, but found new life in beer. Today, the architecture, statues and views of the river make it an artist’s dream.

    5Dubuque, IA
    Iowa’s oldest city, and one of the oldest settlements on the west side of the Mississippi River, French-Canadian fur trader Julien Dubuque arrived in the area in 1785. This ‘All-American City’ has been home to many waves of immigrants, especially Irish and German, creating a thriving downtown and unique Historic Districts.

    6Bettendorf, IA
    Quad Cities is made of 5 neighboring towns and offers Civil War history as well as a blend of communities. A variety of shore excursions is offered at this port, including the Quad City Botanical Center.

    7Burlington, IA
    Spend a day wandering through the scenic streets of Burlington, visiting the local cultural centers and museums.

    8New Madrid, MO
    Head to the New Madrid Historical Museum to learn more about the history of the river and this river town.

    9St. Louis, MO
    What's more iconic in St. Louis than the Gateway Arch? Standing tall on the banks of the Mississippi River, this arch symbolizes the beginning of westward expansion for the United States.

    10River Cruising
    Enjoy the mighty Mississippi! Take a dip in the pool, visit with friends over drinks, or learn about life on the river from the Riverlorian!

    11Memphis, TN
    During a guided tour of Memphis, see it's popular attractions, including Beale Street, the Peabody Hotel. the Sun Studio, and the National Civil Rights Museum.

    12Port of the Mississippi Delta
    Greenville, MS has been an important port along the Mississippi for generations, which you can learn about at the Greenville History Museum. Take a spin on the oldest fully functioning Armitage carousel at the E.E. Bass Cultural Arts Center, and learn about the owner who refused to segregate carousel use. Examine two early 20th century religious buildings: the Hebrew Union Temple built in 1906 and St. Joseph's Catholic Church built in 1907. Plus there's so much more to explore and do in Greenville.

    13Vicksburg, MS
    Civil War history is alive in Vicksburg, Lincoln’s ‘Key to the South.’ This vital river port city has since become a rich historical visit for tourists who want to learn about the battles of Vicksburg, as well as visit their museums.

    14Natchez, MS
    Natchez Indians and the first French explorers shared this beautiful piece of the river for many years. Officially founded in 1716, Natchez is the oldest city on the Mississippi River. Wherever you go, you’ll experience another piece of history, including unique shops, restaurants, museums and the historic homes of Natchez.

    15Nottoway Plantation
    Explore the largest remaining antebellum deep south mansion in this included tour of Nottoway Plantation. This mansion is three floors, 64-bedrooms, and has 22 white square columns, contributing to its nickname, "The White Castle of Louisiana”.

    16Disembark in New Orleans, LA
    Ask about extending your stay in New Orleans, or booking a post-cruise city tour before heading home.

Cabin Categories

Cabin Single Price Double Price
OS Owner's Suites with Exclusive Veranda$20,999 pp
LS Luxury Suites with Private or Open Veranda$17,499 pp
DS Deluxe Suites with Open Veranda$12,599 pp
JS Junior Suites with Open Veranda$11,699 pp
PS Paddlewheel Staterooms$11,499 pp
A Deluxe Outside Stateroomswith Private Veranda$11,399 pp
B Outside Staterooms with Open Veranda$10,999 pp
C Outside Staterooms with Open Veranda$10,299 pp
D Deluxe Outside Staterooms with Bay Window$9,598 pp
E Inside Staterooms$6,299 pp
SD Single Deluxe Staterooms with Open Veranda$8,999
SI Single Inside Staterooms$7,599

Ship Read more about the American Queen

*Prices may vary due to seasonality

American Cuisine

Dining is an uniquely American experience aboard the ship. Local ingredients used to create regional delicasies will charm your tastebuds. In addition to the main dining room, there are also an alternative venue for breakfast, lunch and dinner, as well as 24-hour room service for your convenience.

Pre-Cruise Hotel

The first night of the vacation always includes a hotel night. This ensures that you are in the right city to board your boat on time. You’ll be rested and ready to go! Your breakfast and transfers to the boat are also included.

Hop-On/Hop-Off Bus

You’ll spot the buses right away – they look just like the ship! Two buses travel alongside the boat from port to port. At every port, you’ll be able to board these buses for the Hop-On Hop-Off shore excursions. The bus will have a set route in the town, and you can ride until you see someplace you want to go. Then catch the bus the next time it comes thru.

Book Today

Minneapolis to New Orleans | 16-Day Voyages

Book Now Request More Info

or call 800.578.1479