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Ohio River Cruise: St. Louis to Pittsburgh

Rates & Dates:

Trip Length: 11 Days/ 10 Nights

Prices from: $5,135 pp/do*

Single Price: $6,590 pp

2018 Dates: Jun 17, 27; Jul 7, 17

Ships: The Queen of the Mississippi

Notes: Port charges not included in fare.
*Per Person/Double Occupancy. Special Single Rates apply where listed.

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Paddlewheel chart room

Time to cruise east, leaving the familiar Mississippi behind for the Ohio River! Follow the history of the pioneers who kept pushing the boundaries of American identity in music, culture, architecture, and more. From St. Louis to Pittsburgh (or reverse), this Ohio River cruise will introduce you to the heartland of America.

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From the start of the cruise in St. Louis, you’ll pick up the rhythm of the river. The Queen of the Mississippi will continue that rhythm with the churning paddlewheel and joyful noise of the calliope! Journeying southeast, you’ll visit Paducah, where the Tennessee and Ohio Rivers come together. Where waters meet, so do people, making Paducah rich in history. Walk among the bronze ‘Birds of America’ statues in Henderson, based on the paintings of John James Audubon. Feel the spirit of the South alive in the northern Louisville. Walk through history along the river’s edge. Continue your 11-Day cruise northeast through ports of call in Ohio and Kentucky before disembarking in Pittsburgh, Pennsylvania.

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Day 1: Embark in St. Louis, MO

Day 2: Cape Girardeau, MO

History abounds in this charming river town. Once a popular French trading post, the town’s historic standing is on full display. Visit Civil War sites, the Cape River Heritage Museum, the Red House Interpretive Center, or the commemorative Trail of Tears State Park.

Day 3: Paducah, KY

Where rivers come together, so do people. At the confluence of the Ohio and Tennessee Rivers, you’ll find the building of history quite tangible. Walk through Paducah and remember the Chicasaw village which preceded the town. View the history through the Wall-to-Wall mural collection of more than 50 murals.

Day 4: Henderson, KY

Notable Henderson resident, John James Audubon, has left a legacy of nature in town. His ‘Birds of America’ paintings have been recreated in bronze throughout town. The Audubon Museum Tour is complimentary on this cruise.

Day 5: Scenic River Cruising

Day 6: Louisville, KY

Louisville – pronounced differently depending on where you’re from, but named for King Louis XVI of France and famously home to the Kentucky Derby! The complimentary excursion in Louisville is a visit to the Kentucky Derby Museum and Horse Park, which has footage dating as far back as 1918. If the races are not for you, Louisville is also home to the Louisville Slugger Museum and Factory, or you could visit nearby Clermont to tour the Jim Beam bourbon distillery.

Day 7: Cincinnati, OH

Cincinnati is a fascinating city, full of highlights to excite everyone. If you’re interested in history, you could visit the William Howard Taft National Historic Museum, or the National Underground Railroad Freedom Center. If you’d rather experience natural wonders, take a tour of the Krohn Conservatory – an art deco building built in 1933 with more than 5000 varieties of plants from around the world. If you’re not sure what you want to see, start your day with the complimentary city tour to get a better understanding of the layout of Cincinnati, and an idea of where to go next.

Day 8: Maysville, KY

Maysville is a quaint town, surrounded by picturesque scenery with the sounds of bluegrass music on the wind!

Day 9: Scenic River Cruising

Day 10: Marietta, OH

Named for Marie Antoinette, Marietta shares a metropolitan area with Parkersburg and Vienna, West Virginia, with their location on the Ohio River making it a continually popular stop for tourists and steamboats.

Day 11: Disembark in Pittsburgh, PA

Photo Credit: American Cruise Lines