Sometimes the greatest adventures can be found just outside our own front doors. USA River Cruises offers trips that navigate the coastal waters, rivers, and inland waterways the world over. But some of the most popular and exciting trips take place in the vast nation that we call home: the United States of America.

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We encourage you to look through our U.S.A. offerings. The trips detailed on our website comprise many of the most phenomenal cruises we’ve put together for you. And since they take place right here in the U.S. of A., there’s less travel time involved in getting to the embarkation points, and more time to relax and travel the winding waterways of America.

Here are a few of our more popular offerings — but again we wish to stress how much we’d like you to look over all our offerings in order to tailor a trip that works best for you and your family.

There’s so much to choose from! Consider:

Grand Heartland Cruise: Cruise the length of the Mississippi River on a 14-night southbound trip that starts in St. Paul, Minnesota, and ends in the Big Easy (New Orleans, Louisiana). You’ll cruise down the mighty Mississippi and pass 10 states along the way!

Canyons, Glaciers & Waterfalls: This one’s actually a little off the beaten path — seeing as how it includes hotel stays and five nights aboard an Amtrak train! Visit so many sights and cities: Chicago, Los Angeles, the Grand Canyon (Arizona), Yosemite National Park, Glacier National Park, and more! Whew!

At USA River Cruises, we want to help you plan the trip of a lifetime — and to do it more than once! That’s right, </>all our trips can be considered trips of a lifetime. That’s how diverse, wide-ranging, and spectacular our itineraries are.

Each member of our team is passionate about traveling, and our strong dedication to customer service reflects our longstanding commitment that started the day we first opened our doors in 1996.

Contact USA River Cruises today to speak with a friendly, knowledgeable cruise agent. We want to help you “Imagine the Journey” — and then turn that imagination into reality.

Call us today. We’ll take care of everything.

Maine Coast & Harbors-American Glory

Portland, ME to Bangor, ME

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Cape Codder Cruise-American Glory

Roundtrip Boston

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Rockies to Red Rocks: Denver Return Journey

Roundtrip Denver

  • 7 Nights
  • Please call for information on future dates.
  • From $2,781
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Alaska by Rail & Cruise Featuring Glacier Bay

Sitka to Fairbanks

  • 14 Nights
  • Please call for information on future dates.
  • From $10,126
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New England Islands-American Star

Roundtrip Providence

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Highlights of the Columbia River | 4-Night Cruise

Roundtrip Portland

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Highlights of the Columbia River | 4-night Cruise

Roundtrip Portland

  • 4 Nights
  • April 30, 2025,October 19, 2025,October 23, 2025
  • From $3,125
  • American West
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Columbia & Snake Rivers Cruise – American Harmony

Portland to Clarkston

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Great Lakes & Thunder Bay- Victory II

Roundtrip Chicago

  • 15 Nights
  • May 29, 2025,June 12, 2025
  • From $8,699
  • Victory II
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All 5 Great Lakes – Victory II

Chicago to Toronto

  • 10 Nights
  • May 2, 2025,May 11, 2025,May 20, 2025--
    11 more dates available.
  • From $6,299
  • Victory II
  • New Itinerary for 2025! Pricing Includes Inaugural Savings of $2000 off Per Stateroom!!
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Viking-America’s Great River

St Paul to New Orleans

  • 14 Nights
  • July 5, 2025,September 6, 2025,October 11, 2025
  • From $12,999
  • Viking Mississippi
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New Orleans & Southern Charms

Roundtrip New Orleans

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