Cruises | USA River Cruises

Explore Destinations Across North America and Beyond

Set sail on an unforgettable journey with USA River Cruises. Our curated selection of cruises offers something for every traveler, from the historic waterways of the East Coast to the scenic grandeur of the Pacific Northwest, the vibrant culture of the American South, and the breathtaking Great Lakes. Each itinerary is designed for comfort, exploration, and memorable experiences.

Portland, ME to New York City, NY

Experience the charm of New England’s coast, with stops in iconic cities and picturesque harbors. This cruise is perfect for those who want to explore historic towns and enjoy stunning Atlantic views.

View the details for a Portland, ME to New York City, NY cruise.

Roundtrip St. Petersburg, FL

Discover the beauty of Florida’s Gulf Coast with our roundtrip cruises from St. Petersburg. Enjoy sun-soaked beaches, vibrant local culture, and relaxing days at sea.

Learn more about St. Petersburg, FL cruises.

Montreal to Boston, MA

Sail from the French-Canadian charm of Montreal to the historic harbors of Boston, taking in the best of North America’s northeastern coast.

Learn more about a Montreal to Boston cruise.

New York City to Montreal

This itinerary lets you experience the vibrant cities and scenic waterways between New York and Montreal.

Check out this New York City to Montreal cruise.

New Orleans, LA to Memphis, TN

Journey up the legendary Mississippi River, exploring the music, culture, and history of the American South.

Learn more about this New Orleans to Memphis cruise.

Roundtrip Portland, OR

Experience the natural beauty of the Pacific Northwest, including the Columbia River Gorge and the vibrant city of Portland.

Check out this Columbia River Gorge cruise

Alaska National Parks

Set off on a 18‑day odyssey from Fairbanks to Juneau that combines Denali and Kenai Fjords national parks with an immersive experience on the American Constitution Cruise Ship. Witness glaciers calving, wildlife encounters, and breathtaking Alaskan landscapes at every turn.

Learn more about the Grand Alaska National Parks cruise.

Puget Sound & San Juan Islands Cruise

Enjoy an 8‑day roundtrip voyage from Seattle through the scenic San Juan Islands and Puget Sound — explore historic coastal towns like Friday Harbor and Port Townsend, delight in regional cuisine and wine, and watch for orcas, seals, bald eagles, and more from your private balcony.

Learn more about this cruise in the beautiful Pacific Northwest.

Looking for More Cruise Options?

Browse our full list of cruises to find options on the Mississippi River, Ohio River, Great Lakes, and beyond. Each cruise page offers detailed itineraries, highlights, and booking information to help you plan your perfect getaway.