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Louisville to St. Louis | 9-Day Voyages

This is the heart of America, from the quaint river towns like Owensboro, Kentucky to the bright city skyline of St Louis!

Themed departures for 2021 include: American Culinary Experience on July 4, and Community Outreach on September 26!

Ports of call:

  • Louisville
  • Brandenburg
  • Owensboro
  • Henderson
  • Paducah
  • Cape Girardeau
  • St. Louis

Cruise Details

Clock9 Days & 8 Nights

Double Occupancy from $2,099 pp/do*

CalendarJuly 4, 2021 | September 26, 2021

Book Now Request More Info

or call 800.578.1479

*Per person/double occupancy. Special single rates apply where listed. Excludes port fees.
Itineraries may operate in reverse.

Your Itinerary

    1Boutique Hotel Stay in Louisville, KY

    2Embark in Louisville, KY
    Enjoy your morning in Louisville! We’ll board the ship this afternoon, and depart at 5pm.

    3Brandenburg, KY
    The rolling hills and farmlands surrounding Brandenburg makes it picture perfect! Take a tour General George Patton Museum of Leadership in the fabled Fort Knox.

    4Owensboro, KY
    Owensboro, a hidden river gem, is the 4th largest city in Kentucky. Take in natural wonder and beauty at the Western Kentucky Botanical Garden or the Owensboro Area Museum of Science and History. Or experience manmade beauty at the Owensboro Museum of Fine Art or the International Bluegrass Music Museum!

    5Henderson, KY
    Explore the homes of Jame Audubon and W.C. Handy, and walk the streets of the waterfront in the downtown area, you'll find it's an artistic town!

    6Paducah, KY
    Paducah sits at the crossroads of the Mississippi, Ohio, Cumberland and Tennessee Rivers. Popular stops in Paducah include the National Quilt Museum, Lloyd Tilghman House and Civil War Museum, and the Paducah Railroad Museum!

    7Cape Girardeau, MO
    You'll be wandering the same streets that Mark Twain, William Clark and Meriwether Lewis all walked down long, long ago. Hospitality is alive in this town, and you'll find many treasures here.

    8River Cruising

    9Disembark in St. Louis
    Ask about extending your stay with a post-cruise hotel stay!


Cabin Categories

Cabin Single Price Double Price
Owner's Suite$6,999 pp
Loft Suite$6,099 pp
Deluxe Suite$6,099 pp
Veranda Suite$4,199 pp
Inside Suite$2,099 pp

Ship Read more about the American Duchess

*Prices may vary due to seasonality

American Cuisine

Dining is an uniquely American experience aboard the ship. Local ingredients used to create regional delicasies will charm your tastebuds. In addition to the main dining room, there are also an alternative venue for breakfast, lunch and dinner, as well as 24-hour room service for your convenience.

Pre-Cruise Hotel

The first night of the vacation always includes a hotel night. This ensures that you are in the right city to board your boat on time. You’ll be rested and ready to go! Your breakfast and transfers to the boat are also included.

Hop-On/Hop-Off Bus

You’ll spot the buses right away – they look just like the ship! Two buses travel alongside the boat from port to port. At every port, you’ll be able to board these buses for the Hop-On Hop-Off shore excursions. The bus will have a set route in the town, and you can ride until you see someplace you want to go. Then catch the bus the next time it comes thru.

Book Today

Louisville to St. Louis | 9-Day Voyages

Book Now Request More Info

or call 800.578.1479